On the national scene, critics have charged that two major drug Companies downplayed the side effects of their drugs before pulling them off the market. Merck in 2004 pulled Vioxx, its popular anti-arthritis drug, because it had been shown to increase the risk of heart attack and Stroke, as M. Paul Jackson noted in Tuesday's Journal. And Pfizer pulled Bextra, its anti-arthritis drug, because it had been shown to increase the risk of heart disease.
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